Thursday, January 8, 2009

On Pseudoephedrine

Several common syntheses of methamphetamine. Note: ephedrine/pseudoephedrine are featured in 4 out of the 6. The Birch reduction, using liquid ammonia and lithium metal, is probably my favorite because it's also known as the Nazi method.

Psudoephedrine (the drug in Sudafed) is a wonderful chemical. It is very effective at reducing nasal congestion by 1) constricting the blood vessels in mucus membranes, reducing mucus production and 2) promoteing er… more free flowing congestion. Psudoephedrine is so wonderful that it does all this without causing the drowsiness associated with antihistamines like diphenhydramine (Benadryl).

Unfortunately, access to pseudoephedrine has been increasing restricted because it is one of the primary precursor chemicals used in methamphetamine synthesis (see above). The fact that psudoephedrine is now “over the counter” rather than “off the shelf” is not much more than a minor hindrance to the avid meth enthusiast or determined nasal decongestant user. Unfortunately, the pill-pushers that be, have begun to promote a new nasal decongestant, phenylephrine as an “off the shelf” alternative to psudoephedrine.

What’s the big deal? You ask. Why the chemistry lesson? Well, recent research has shown that at the FDA’s advised dosage, phenylephrine is not a more effective nasal decongestant than a placebo. My point is this: next time you have a stuffy nose and are in need of relief, don’t waste your money on nasal decongestants with phenylephrine (products like Sudafed PE, or generic non-psudoephedrine containing pills) they don’t work.

Now, that’s some nerdy consumer advocacy if I do say so myself.

7 comments:

Anonymous said...

With regard to psudoephedrine Hcl,& properties that make the precursor,See ?production of asian ephedrine Hcl.it would appear these sites are dangerous,they give instructions that go around the block,as oppossed to a direct )& safe conclusion.theyre advice as to ventilation.use nthe by product that occurres from Ephedrine Hcl production.If you intend to mislead i shall reveal what one should do.The shulgins also would non to pleased were i to reveal how simple one may convert this bi product which may give those who are not B pharm level,a way to realise their goals safely & without all the red herrings.Theyre a dangerouse lot experts.al-??????@.

Anonymous said...

psdo-ephedrine-deoxyephedrine.methamphetamine hcl As written in the 1963 codex. Methylamphetamine hcl is(+)-N-alpha-dimethylphethylamine hcl it is made directly by reducing psudo-ephedrine,obtained from the production of L ephedrine,bp with hydriodic acid and phosphorus,and converting the powder to the hydrochloride.\it occurres as white odourless crystals or crystaline powder with a bitter taste,it has a melting point of 172 to 174%.Its really quite easy,follow the recipe and ENJOY

Alchemist@ said...

it really is that easy,the only problemb may be the hydriodid acid,phosphors easily obtained,stop following the advice of those who appear to be the real deal,they just dont want you knowing what they know.So if your lookin for these illusively guarded secrets,im on it,one in the bag & more besides,and methylamine hcl i have made a ton of this stuff,it was almost to easy to be true,at 1st but as with many others currently in the pot phenethylamine,is abundant,it simply takes some hrs to realise.Any intersted in knowing how see deoxyephedrine,above

Alchemist said...

Has anyone any idea as to the chemical similatities that exists between Atropine from belladona & hyoscine alkaloids,the only real difference is that one has an extra molecule of h2o,water.Any suggestions to this & how one may procceed if possible.Can someone tell me this lithium & ammonia method called the birch method?

Alchemist@ said...

apologies for the previouse post ,i meant does anyone know the reason that cocaine & atropine,WELL SEE FOR YOURSELVES

Anonymous said...

habi believe i have a method to realise phenethylamine.its relativly safe but it requires 8-9hrs low heat constant agitation,use a magnetic stirrer or you could do it manually but i dont recommend it,use your initiative & be sure to keep the heat below 100%c for this period 7 then???tell me about the lithium/ammonia method.for the remaining phenethylamine procedure,great yields to

Elite Nutrition said...

Ephedrine Hcl is a very
strong fat burner but you have to be careful when using. One dose a day of 30
mgs is fine for two weeks then with one or two weeks off as the body will start
to get used to it. This is when the user feels they have to increase the dose,
but like I said should discontinue use.